SCHEMBL9320141

SCHEMBL9320141

C=C(C(=O)NC(C)C)N(CC)CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
FAAH O00519 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 3/20 0.33
EPHX1 P07099 1/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32
IDE P14735 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MMP1 P03956 2/20 0.31
MMP2 P08253 2/20 0.31
MMP8 P22894 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319824 0.78 TSHR (0.41) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL9319967 0.73 ALDH1A1 (0.35) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL12086356 0.73 PTGES (0.40) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL8643965 0.71 TSHR (0.39) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL9319960 0.71 EGFR (0.39) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL10659222 0.69 TSHR (0.64) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL10337837 0.69 FAAH (0.42) TSHRKMT2AFAAHALDH1A1KDM4E
SCHEMBL28422625 0.68 MEN1 (0.44) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL10760000 0.68 ALDH1A1 (0.38) TSHRMEN1KMT2AFAAHMAPK1
SCHEMBL10937185 0.68 EPHX1 (0.44) TSHREPHX1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428970-B1 Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride BASF AG (DE) 1994-01-19 EP disclosed
EP-0428970-A1 Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride BASF Aktiengesellschaft (DE) 1991-05-29 EP disclosed
US-4647606-A Blend of rapid set asphaltic emulsion with slow set asphalt emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1987-03-03 US disclosed
EP-0113038-B1 PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS BASF Aktiengesellschaft (DE) 1986-09-10 EP disclosed
US-4547225-A Additives for hot mix asphalt OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-10-15 US disclosed
US-4520210-A ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION BASF AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed
EP-0082056-B1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-05-22 EP disclosed
EP-0113038-A2 Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids BASF Aktiengesellschaft (DE) 1984-07-11 EP disclosed
US-4456633-A Chip seal technique employing blends of asphaltic emulsions OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-06-26 US disclosed
US-4436864-A Aqueous emulsions of acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4436767-A Slurry seal method using acrylamide and rubber modified asphaltic emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4419489-A Easily emulsifiable acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-12-06 US disclosed
US-4394481-A Cationic arcylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-07-19 US disclosed
WO-1983002115-A1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS CORNING FIBERGLASS CORP (US) 1983-06-23 WO disclosed
EP-0082056-A1 Cationic acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-06-22 EP disclosed
US-4383081-A Cationic acrylamide chemically modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-05-10 US disclosed