SCHEMBL9320157

SCHEMBL9320157

c1cc(NCCCC2CO2)ccc1Cc1ccc(NCCCC2CO2)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
MGLL Q99685 2/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
PRSS1 P07477 4/20 0.33
CHRM2 P08172 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
F2 P00734 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
TMPRSS6 Q8IU80 2/20 0.32
ST14 Q9Y5Y6 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321231 0.95 ALDH1A1 (0.36) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL22204395 0.82 ALDH1A1 (0.57) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL7535852 0.78 LMNA (0.38) ALDH1A1MEN1KMT2ALMNAMGLL
Diphenylmethane SCHEMBL9322223 0.76 MEN1 (0.47) MEN1KMT2AMGLLCHRM2
SCHEMBL19901809 0.72 KCNH3 (0.36) MAPTMEN1KMT2AMGLLBCHE
Diphenylmethane SCHEMBL9321214 0.71 MEN1 (0.46) ALDH1A1MEN1KMT2AMGLLCHRM2
SCHEMBL409525 0.71 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL13867475 0.70 MAPT (0.48) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL2492317 0.70 LMNA (0.44) ALDH1A1MAPTLMNABCHEACHE
SCHEMBL13876474 0.70 MAPT (0.43) ALDH1A1MAPTPRSS1F2PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336391-B1 Reversibly color-changeable materials TEIJIN LTD (JP) 1994-01-26 EP disclosed
US-5068062-A Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material TEIJIN LIMITED (JP) 1991-11-26 US disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed