Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320263 | 0.94 | THRA (0.43) | THRATHRB | |
| SCHEMBL9321693 | 0.94 | THRA (0.43) | THRATHRB | |
| SCHEMBL9320967 | 0.90 | EPHX2 (0.47) | EPHX2LTA4HPTGER3THRATHRB | |
| SCHEMBL9320976 | 0.85 | LTA4H (0.42) | EPHX2LTA4HPTGER3 | |
| SCHEMBL9321717 | 0.84 | THRA (0.47) | PTGER3THRATHRB | |
| SCHEMBL9320996 | 0.84 | THRA (0.47) | PTGER3THRATHRB | |
| SCHEMBL9320971 | 0.80 | LTA4H (0.47) | EPHX2LTA4HPTGER3THRATHRB | |
| SCHEMBL9321064 | 0.79 | — | — | |
| SCHEMBL10701856 | 0.79 | SIGMAR1 (0.49) | EPHX2 | |
| SCHEMBL9321888 | 0.78 | EPHX2 (0.44) | EPHX2LTA4HPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |