Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15682759 | 0.83 | SLC29A1 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL110077 | 0.80 | — | — | |
| SCHEMBL8081024 | 0.76 | LTA4H (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL3731822 | 0.75 | CHRM2 (0.42) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL16991083 | 0.74 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9542064 | 0.74 | CHRNB2 (0.30) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17293544 | 0.72 | MEN1 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL18572064 | 0.72 | LMNA (0.51) | LMNAALDH1A1MAPTPIK3CDSLC6A4 | |
| SCHEMBL320363 | 0.71 | MAPT (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL9025201 | 0.71 | LMNA (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102037038-B | Polyurethane foam-forming compositions containing polysilsesquioxane cell opening agents | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-10-08 | — | — | CN | disclosed |
| CN-102037038-A | Polyurethane foam-forming compositions containing polysilsesquioxane cell opening agents | MOMENTIVE PERFORMANCE MAT INC | 2011-04-27 | — | — | CN | disclosed |
| EP-0342439-B1 | Process for the aftertreatment of dyed textile materials | BAYER AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0504448-A1 | Process for the preparation of polyurea elastomerbased foamed masses | Huntsman International Trading Deutschland GmbH (DE) | 1992-09-23 | — | — | EP | disclosed |
| US-4964875-A | Process for after-treatment of dyed polyamide textile materials with polyurethane containing quaternary ammonium groups | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |