Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL11162488 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BSLC6A4LMNAADRB2 | |
| SCHEMBL13452617 | 0.82 | MTNR1A (0.61) | MTNR1AMTNR1BSLC6A4LTA4H | |
| SCHEMBL8854035 | 0.81 | SIGMAR1 (0.48) | MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL3953294 | 0.80 | MTNR1A (0.59) | MTNR1AMTNR1BSLC6A4LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL11128673 | 0.78 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A4ADRB2ADRB1 | |
| SCHEMBL7566883 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BSLC6A4LMNALTA4H | |
| SCHEMBL120055 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BSLC6A4LMNALTA4H | |
| SCHEMBL17892031 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BSLC6A4LMNALTA4H | |
| SCHEMBL9870637 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A4LMNALTA4H | |
| SCHEMBL9870647 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A4LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427480-B1 | 2-Hydroxy-3-phenoxypropylamino compounds | ICI PLC (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0427480-A1 | 2-Hydroxy-3-phenoxypropylamino compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-15 | — | — | EP | disclosed |