Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | AOC2 | O75106 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320812 | 0.93 | RIPK1 (0.31) | RIPK1MAOAMAOBAOC2SCN9A | |
| SCHEMBL9322886 | 0.93 | CDK2 (0.32) | RIPK1MAOAMAOBAOC2SCN9A | |
| SCHEMBL9320191 | 0.92 | CDK2 (0.33) | RIPK1SCN9AJAK2JAK1TYK2 | |
| SCHEMBL9321633 | 0.92 | CDK2 (0.33) | RIPK1SCN9AJAK2JAK1TYK2 | |
| SCHEMBL11370619 | 0.75 | PSIP1 (0.32) | — | |
| SCHEMBL21293714 | 0.75 | JAK2 (0.31) | JAK2JAK1TYK2 | |
| SCHEMBL21293353 | 0.74 | AOC2 (0.31) | MAOAMAOBAOC2 | |
| SCHEMBL11375532 | 0.70 | LOXL2 (0.37) | RIPK1 | |
| SCHEMBL22494208 | 0.69 | — | — | |
| SCHEMBL11382801 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308830-A | Low dosage; nonphytotoxic to crops; pre- and postemergence | ROHM AND HAAS COMPANY (US) | 1994-05-03 | — | — | US | disclosed |