Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320976 | 0.91 | LTA4H (0.42) | LTA4HPTGER3EPHX2HTR1AS1PR2 | |
| SCHEMBL9320967 | 0.86 | EPHX2 (0.47) | LTA4HPTGER3EPHX2HTR1ATRPV1 | |
| SCHEMBL9321717 | 0.81 | THRA (0.47) | PTGER3THRATHRBS1PR2S1PR1 | |
| SCHEMBL9320996 | 0.81 | THRA (0.47) | PTGER3THRATHRBS1PR2S1PR1 | |
| SCHEMBL9320972 | 0.80 | EPHX2 (0.43) | LTA4HPTGER3EPHX2THRATHRB | |
| SCHEMBL9321037 | 0.79 | EPHX2 (0.57) | EPHX2TRPV1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9321046 | 0.79 | EPHX2 (0.57) | EPHX2TRPV1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9321040 | 0.78 | FAAH (0.65) | EPHX2TRPV1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9321739 | 0.78 | EPHX2 (0.51) | LTA4HEPHX2TRPV1CYP1A2CYP3A4 | |
| SCHEMBL6700457 | 0.78 | EPHX2 (0.51) | LTA4HEPHX2TRPV1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |