SCHEMBL9320985

SCHEMBL9320985

O=S(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
HPGD P15428 2/20 0.39
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C19 P33261 1/20 0.38
PPARA Q07869 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK1 P28482 2/20 0.36
MMP13 P45452 1/20 0.35
ATF4 P18848 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395603 0.80 HPGD (0.41) MEN1KMT2ACA1CA2CA9
SCHEMBL28499782 0.78 CA1 (0.39) MEN1KMT2ACA1CA2CA9
SCHEMBL223148 0.74 MEN1 (0.50) MEN1KMT2ACA1CA2CA9
SCHEMBL7747956 0.74 ALDH1A1 (0.50) MEN1KMT2AMAOAMAOBHPGD
SCHEMBL31634387 0.74 LMNA (0.42) MEN1KMT2ACA1CA2CA9
SCHEMBL31634389 0.74 LMNA (0.42) MEN1KMT2ACA1CA2CA9
SCHEMBL8831132 0.74 IDO1 (0.33)
SCHEMBL776590 0.74 ACHE (0.48) MEN1KMT2ACA1CA2CA9
SCHEMBL11087027 0.74 CA1 (0.58) CA1CA2CA9CYP2A6CYP3A4
SCHEMBL775482 0.72 LTA4H (0.45) CA1CA2CA9MAOACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0317207-B1 Production of 2,3'-anhydro-2'deoxyuridine derivatives SCOTIA HOLDINGS PLC (GB) 1994-02-02 EP claimed
US-4937329-A Production of 2,3'-anhydro-2'-deoxyuridine derivatives EFAMOL HOLDINGS P.L.C. (GB) 1990-06-26 US claimed
EP-0317207-A2 Production of 2,3'-anhydro-2'deoxyuridine derivatives SCOTIA HOLDINGS PLC (GB) 1989-05-24 EP claimed
JP-1258696-A None JP disclosed
EP-0317207-B1 Production of 2,3'-anhydro-2'deoxyuridine derivatives SCOTIA HOLDINGS PLC (GB) 1994-02-02 EP disclosed
US-4937329-A Production of 2,3'-anhydro-2'-deoxyuridine derivatives EFAMOL HOLDINGS P.L.C. (GB) 1990-06-26 US disclosed
JP-H01258696-A PRODUCTION OF 2,3'-ANHYDRO-2'-DEOXYURIDINE DERIVATIVE KINGS COLLEGE LONDON 1989-10-16 JP disclosed
EP-0317207-A2 Production of 2,3'-anhydro-2'deoxyuridine derivatives SCOTIA HOLDINGS PLC (GB) 1989-05-24 EP disclosed
US-4465851-A ANTIALLERGENS, ENZYME INHIBITORS NIPPON CHEMIPHAR CO., LTD. (JP) 1984-08-14 US disclosed
US-4433152-A ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT NIPPON CHEMIPHAR CO., LTD. (JP) 1984-02-21 US disclosed