Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321412 | 0.94 | SMN1; SMN2 (0.48) | BCHESMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL9324758 | 0.86 | LTA4H (0.42) | BCHESMN1; SMN2HSD17B10ALDH1A1TP53 | |
| SCHEMBL9323712 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2HSD17B10ALDH1A1KMT2AGNAI3 | |
| SCHEMBL9322401 | 0.82 | GAA (0.40) | SMN1; SMN2HSD17B10ALDH1A1TP53LTA4H | |
| SCHEMBL9323677 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10KMT2ATP53GNAI3 | |
| SCHEMBL9324616 | 0.80 | GAA (0.46) | ALDH1A1KMT2ALTA4H | |
| SCHEMBL9322261 | 0.80 | HRH3 (0.36) | SMN1; SMN2TP53 | |
| SCHEMBL9323550 | 0.78 | TP53 (0.39) | SMN1; SMN2TP53USP2 | |
| SCHEMBL9322225 | 0.78 | THRA (0.40) | BCHESMN1; SMN2HSD17B10ALDH1A1TP53 | |
| SCHEMBL9323599 | 0.76 | BCHE (0.49) | BCHESMN1; SMN2HSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |