Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321324 | 0.93 | SMN1; SMN2 (0.47) | BCHESMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL9323599 | 0.86 | BCHE (0.49) | BCHESMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL9322436 | 0.85 | SMN1; SMN2 (0.50) | BCHESMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL9322204 | 0.84 | SPHK1 (0.46) | BCHEKCNH2GNAI3GNAO1GNAI1 | |
| SCHEMBL3933177 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 | |
| SCHEMBL7131574 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 | |
| SCHEMBL7135236 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 | |
| SCHEMBL7137293 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 | |
| SCHEMBL474297 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 | |
| SCHEMBL30444781 | 0.80 | BCHE (0.68) | BCHESMN1; SMN2KCNH2GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |