Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323599 | 0.93 | BCHE (0.49) | SMN1; SMN2ALDH1A1BCHEKMT2AMEN1 | |
| SCHEMBL9322294 | 0.93 | BCHE (0.50) | SMN1; SMN2ALDH1A1BCHEKMT2AMEN1 | |
| SCHEMBL9322436 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1BCHEKMT2AMEN1 | |
| SCHEMBL9323743 | 0.84 | THRA (0.40) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3937676 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1BCHEKMT2AMEN1 | |
| SCHEMBL9322337 | 0.81 | KCNA3 (0.43) | HRH3 | |
| SCHEMBL9323544 | 0.77 | KCNA3 (0.40) | HRH3 | |
| SCHEMBL9322512 | 0.77 | HRH3 (0.40) | HRH3 | |
| SCHEMBL9321412 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1BCHEKMT2AMEN1 | |
| SCHEMBL9322277 | 0.74 | SIGMAR1 (0.44) | KMT2AMEN1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |