Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321324 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9322294 | 0.85 | BCHE (0.50) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9323599 | 0.85 | BCHE (0.49) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3937676 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9322325 | 0.80 | KCNA3 (0.41) | — | |
| SCHEMBL9323743 | 0.75 | THRA (0.40) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9323712 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4732168 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9321412 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1438742 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1LMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |