Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321324 | 0.93 | SMN1; SMN2 (0.47) | BCHESMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL9322294 | 0.86 | BCHE (0.50) | BCHESMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL9322436 | 0.85 | SMN1; SMN2 (0.50) | BCHESMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL9323743 | 0.80 | THRA (0.40) | SMN1; SMN2ALDH1A1LTA4HHSD17B10 | |
| SCHEMBL9322512 | 0.79 | HRH3 (0.40) | — | |
| SCHEMBL9322337 | 0.77 | KCNA3 (0.43) | — | |
| SCHEMBL9322356 | 0.76 | BCHE (0.47) | BCHESMN1; SMN2KMT2AALDH1A1LTA4H | |
| SCHEMBL14155738 | 0.75 | SMN1; SMN2 (0.55) | BCHESMN1; SMN2KMT2AALDH1A1LTA4H | |
| SCHEMBL3937676 | 0.75 | SMN1; SMN2 (0.59) | BCHESMN1; SMN2KMT2AALDH1A1LTA4H | |
| SCHEMBL14155739 | 0.75 | SMN1; SMN2 (0.55) | BCHESMN1; SMN2KMT2AALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |