SCHEMBL9323558

SCHEMBL9323558

[c]1nc2c(-c3ccncc3)cccc2[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.47
IMPDH2 P12268 4/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
PKN1 Q16512 4/20 0.34
PKN2 Q16513 4/20 0.34
GSK3B P49841 2/20 0.34
DYRK1A Q13627 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NFATC1 O95644 1/20 0.34
PIM1 P11309 2/20 0.33
PRKACA P17612 2/20 0.33
RPS6KB1 P23443 2/20 0.33
PRKCZ Q05513 2/20 0.33
PLK4 O00444 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3226179 0.89 KDR (0.35) PIK3CDGSK3BDYRK1APRKACARPS6KB1
SCHEMBL434158 0.86 METAP2 (0.43) MAPK1HSD17B10DYRK1AALDH1A1PLK4
SCHEMBL4623912 0.80 METAP2 (0.35) MAPK1HSD17B10MGAMGAASI
SCHEMBL5512822 0.77
SCHEMBL1941381 0.73 MGAM (0.40) HSD17B10MGAMGAASIMGAM2
SCHEMBL4190285 0.73 CSNK1A1 (0.42) PIK3CDKDM4EALDH1A1IDO1
SCHEMBL6489268 0.71 BCHE (0.40) MAPK1HSD17B10GAAGSK3BKDM4E
SCHEMBL4988840 0.71 METAP2 (0.30)
SCHEMBL16267389 0.71 LMNA (0.45) ALDH1A1NOTUMLMNA
SCHEMBL810755 0.71 METAP1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321190-B1 Silver halide color photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1994-02-09 EP disclosed