Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | SI | P14410 | 3/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434158 | 0.86 | METAP2 (0.43) | METAP2ALDH1A1MAPK1HSD17B10PLK4 | |
| SCHEMBL3226179 | 0.86 | KDR (0.35) | METAP2PLK4AURKADAPK3PRKD3 | |
| SCHEMBL6489268 | 0.86 | BCHE (0.40) | METAP2GAAALDH1A1TSHRMAPK1 | |
| SCHEMBL4116491 | 0.82 | PARP14 (0.45) | — | |
| SCHEMBL9323558 | 0.80 | PIK3CD (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3638684 | 0.78 | KDM4E (0.49) | GAAALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL5669337 | 0.77 | — | — | |
| SCHEMBL4190285 | 0.77 | CSNK1A1 (0.42) | ALDH1A1KDM4EMEN1MTORCSNK1A1 | |
| SCHEMBL1941381 | 0.77 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4363073 | 0.76 | BCHE (0.33) | ALDH1A1MAPK1HSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353642-B1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AMPHIPHILIC COPOYLMER COMPRISING 2-ACRYLAMIDO-2-PROPANESULFONIC AND (METH)ACRYLATES | OREAL (FR) | 2008-05-07 | — | — | EP | claimed |
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-7045120-B2 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | L'OREAL (FR) | 2006-05-16 | — | — | US | claimed |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| CN-107847414-B | Composition comprising a UV screening agent, an anionically crosslinked hydrophilic polymer, a surfactant having an HLB less than or equal to 5, and a siloxane copolymer | 欧莱雅 | 2021-09-10 | — | — | CN | disclosed |
| EP-3185843-B1 | GEL COMPOSITION AND GEL COMPRISING A UV FILTER | OREAL (FR) | 2021-08-11 | — | — | EP | disclosed |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | L'OREAL (FR) | 2020-11-19 | — | — | US | disclosed |
| CN-111343968-A | Composition comprising at least one acrylic polymer and at least one insoluble organic masking agent | 莱雅公司 | 2020-06-26 | — | — | CN | disclosed |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | disclosed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | disclosed |
| EP-1353642-A1 | AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS WITH AT LEAST ONE MONOMER HAVING ETHYLENIC UNSATURATION WITH A SULPHONIC GROUP AND COMPRISING A HYDROPHOBIC PART | L'OREAL (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | disclosed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | L'OREAL (FR) | 2003-07-10 | — | — | US | disclosed |
| WO-2002055045-A1 | AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS WITH AT LEAST ONE MONOMER HAVING ETHYLENIC UNSATURATION WITH A SULPHONIC GROUP AND COMPRISING A HYDROPHOBIC PART | L'OREAL (FR) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | CUTA, HNRNPU, ERCC5 | METAP2 3900/4885NUDT1 1496/4885MGAM 3915/4885 |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | PCNA, ERCC1, XRCC6 | METAP2 1708/4885NUDT1 1576/4885MGAM 893/4885 |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | CUTA, DSG1, PCNA | METAP2 3343/4885NUDT1 4147/4885MGAM 4182/4885 |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | METAP2 3422/4885NUDT1 1053/4885MGAM 4833/4885 |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | METAP2 3366/4885NUDT1 1572/4885MGAM 4250/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | METAP2 3366/4885NUDT1 1572/4885MGAM 4250/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | METAP2 1877/4885NUDT1 2700/4885MGAM 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.