SCHEMBL434158

SCHEMBL434158

[c]1nc2c(-c3ccccc3)cccc2[nH]1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.43
CLK4 Q9HAZ1 3/20 0.40
LIMK1 P53667 2/20 0.40
PLK4 O00444 1/20 0.40
MAPK9 P45984 1/20 0.40
AKT3 Q9Y243 1/20 0.40
CNR2 P34972 7/20 0.37
LTK P29376 2/20 0.35
DYRK1B Q9Y463 2/20 0.35
MAP4K4 O95819 1/20 0.35
CSF1R P07333 1/20 0.35
FGFR1 P11362 1/20 0.35
PDGFRA P16234 1/20 0.35
KDR P35968 1/20 0.35
MAPK8 P45983 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CDK5 Q00535 1/20 0.35
ACVR1 Q04771 1/20 0.35
TNK2 Q07912 1/20 0.35
AURKB Q96GD4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3226179 0.92 KDR (0.35) METAP2CLK4LIMK1PLK4MAPK9
SCHEMBL4623912 0.86 METAP2 (0.35) METAP2CLK4PLK4MAPK9MAP4K4
SCHEMBL9323558 0.86 PIK3CD (0.47) CLK4PLK4AKT3MAP4K4FGFR1
SCHEMBL6489268 0.77 BCHE (0.40) METAP2CDK5ALDH1A1HPGDHSD17B10
SCHEMBL5512822 0.76
SCHEMBL5946637 0.76 PDGFRB (0.52) CLK4MAP4K4PDGFRACYP2A6DYRK1A
SCHEMBL4988840 0.74 METAP2 (0.30) METAP2
SCHEMBL3638684 0.74 KDM4E (0.49) CLK4PLK4MAPK9MAP4K4CSF1R
SCHEMBL4116491 0.74 PARP14 (0.45)
SCHEMBL9110854 0.73 ALDH1A1 (0.36) CDK5ALDH1A1HPGDHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO claimed
CN-117242066-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-12-15 CN claimed
CN-115368390-A Single-boron organic compound as OLED (organic light emitting diode) doping material and organic electroluminescent device comprising same 江苏三月科技股份有限公司 2022-11-22 CN claimed
CN-108129429-B Naphthalene benzofuran derivative and preparation method thereof 张家港九力新材料科技有限公司 2021-07-20 CN claimed
CN-110650961-A PARP inhibitor, pharmaceutical composition, preparation method and application thereof 广州丹康医药生物有限公司 2020-01-03 CN claimed
EP-2581365-B1 Heterocyclic compound, organic light-emitting diode comprising the heterocyclic compound, and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO LTD (KR) 2019-10-16 EP claimed
US-20180294417-A1 FLUORENE-CARBAZOLE DERIVATIVES AND PHOSPHORESCENT ORGANIC ELECTROLUMINESCENT DEVICES WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-10-11 US claimed
US-20180291263-A1 SPIROFLUORENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-10-11 US claimed
US-9865828-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-09 US claimed
US-9570687-B2 Organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-14 US claimed
US-20140054558-A1 CASCADE-TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2014-02-27 US claimed
US-20130099206-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE HETEROCYCLIC COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-04-25 US claimed
US-20130099208-A1 CONDENSED-CYCLIC COMPOUND, METHOD FOR PREPARING THE CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED-CYCLIC COMPOUND SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-04-25 US claimed
EP-2581365-A1 Heterocyclic compound, organic light-emitting diode comprising the heterocyclic compound, and flat panel display device comprising the organic light-emitting diode Samsung Display Co., Ltd. (KR) 2013-04-17 EP claimed
US-20130087768-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE HETEROCYCLIC COMPOUND, AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-04-11 US claimed
EP-2477979-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS Nitto Denko Corporation (JP) 2012-07-25 EP claimed
JP-2011528324-A 2011-11-17 JP claimed
EP-2307520-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES Merck Patent GmbH (DE) 2011-04-13 EP claimed
WO-2011034967-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-24 WO claimed
WO-2010006680-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2010-01-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130099208-A1 CONDENSED-CYCLIC COMPOUND, METHOD FOR PREPARING THE CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED-CYCLIC COMPOUND C1R, CRY1, C9 METAP2 4860/4885CLK4 600/4885LIMK1 1619/4885
US-20180294417-A1 FLUORENE-CARBAZOLE DERIVATIVES AND PHOSPHORESCENT ORGANIC ELECTROLUMINESCENT DEVICES FOXO3, TEC, GDI2 METAP2 4109/4885CLK4 3539/4885LIMK1 2006/4885
US-20180291263-A1 SPIROFLUORENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, GFPT1, TRPA1 METAP2 3898/4885CLK4 4357/4885LIMK1 937/4885
US-20130087768-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE HETEROCYCLIC COMPOUND, AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE DRD1, DRD2, DRD3 METAP2 4151/4885CLK4 1250/4885LIMK1 335/4885
US-20130099206-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE HETEROCYCLIC COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE DRD1, HTR1D, DRD4 METAP2 4017/4885CLK4 1006/4885LIMK1 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.