Water

Water

SCHEMBL932356

CCCC[Sn+](CCCC)CCCC.[OH-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
LMNA P02545 3/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC22A1 O15245 3/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
APAF1 O14727 1/20 0.30
HSP90AA1 P07900 1/20 0.30
RAD52 P43351 1/20 0.30
DNM1 Q05193 4/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30633598 0.96 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL6750642 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL910536 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL411338 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride Ion SCHEMBL394141 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Hydrogen Sulfide SCHEMBL10730186 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Hydrochloric Acid SCHEMBL1130 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL2345 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Hydrochloric Acid SCHEMBL7928153 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Iodide SCHEMBL578857 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812501-A Preparation method of lipoic acid 山东新时代药业有限公司 2024-10-22 CN claimed
CN-113710718-B Stabilized silane-modified polymer compositions and methods 迈图高新材料公司 2024-06-25 CN claimed
CN-112679513-B Method for preparing key intermediate of koji Bei Ti 南通诺泰生物医药技术有限公司 2023-08-25 CN claimed
CN-112679512-B Trabectedin intermediate and preparation method thereof 南通诺泰生物医药技术有限公司 2023-08-25 CN claimed
EP-3956376-A1 STABLE SILANE MODIFIED POLYMER COMPOSITION AND METHOD Momentive Performance Materials Inc. (US) 2022-02-23 EP claimed
CN-113710718-A Stable silane-modified polymer compositions and methods 迈图高新材料公司 2021-11-26 CN claimed
US-20200332052-A1 STABILE SILANE MODIFIED POLYMER COMPOSITION AND METHOD MOMENTIVE PERFORMANCE MATERIALS INC. 2020-10-22 US claimed
WO-2020214935-A1 STABILE SILANE MODIFIED POLYMER COMPOSITION AND METHOD MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-10-22 WO claimed
US-7863398-B2 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-04 US claimed
EP-2134767-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS Momentive Performance Materials Inc. (US) 2009-12-23 EP claimed
US-20080242825-A1 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US claimed
WO-2008118460-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-02 WO claimed
US-5627301-A Process for the preparation of mono-alkylcarbonate of bisphenols COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1997-05-06 US claimed
JP-57168964-A None JP disclosed
WO-2026104544-A1 EXO-VINYLENE CARBONATE COMPOUNDS AS PRECURSORS FOR ISOCYANATE-FREE URETHANE-TYPE POLYMERS BASF SE (DE) 2026-05-21 WO disclosed
EP-4745170-A1 METHOD FOR PREPARING A URETHANE GROUP-CONTAINING POLYMER BASF SE (DE) 2026-05-20 EP disclosed
US-4018724-A ZINC SALT OF 2-MERCAPTOBENZOTHIAZOLE THE GENERAL TIRE & RUBBER COMPANY (US) 1977-04-19 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-3978011-A DISCOLORATION INHIBITION, ZINC SALT OF DITHIOCARBAMIC ACID THE GENERAL TIRE & RUBBER COMPANY (US) 1976-08-31 US disclosed
US-3933940-A Mercaptan blocked thermosetting copolymers PPG INDUSTRIES, INC. (US) 1976-01-20 US disclosed