Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204507 | 0.81 | MEN1 (0.47) | THRBERCC5FEN1ALDH1A1RAB9A | |
| SCHEMBL7689188 | 0.79 | GAA (0.44) | MEN1KMT2A | |
| SCHEMBL8488611 | 0.77 | ERCC5 (0.59) | THRBERCC5FEN1ALDH1A1RAB9A | |
| SCHEMBL9325335 | 0.75 | ALDH1A1 (0.47) | ENPP3ENPP1FLT1FLT4KDR | |
| SCHEMBL8700100 | 0.75 | TSHR (0.50) | FLT1FLT4KDRPPARAALDH1A1 | |
| SCHEMBL9324471 | 0.73 | PPARA (0.34) | ENPP3ENPP1FLT1FLT4KDR | |
| SCHEMBL9324464 | 0.73 | PPARA (0.34) | ENPP3ENPP1FLT1FLT4KDR | |
| SCHEMBL8492085 | 0.73 | F10 (0.41) | FLT1FLT4KDRERCC5FEN1 | |
| SCHEMBL8724610 | 0.72 | ERCC5 (0.38) | THRBERCC5FEN1ALDH1A1RAB9A | |
| SCHEMBL8489200 | 0.71 | KDM4E (0.44) | ALDH1A1RAB9AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |