Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPRG | P23470 | 3/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488611 | 0.79 | ERCC5 (0.59) | ERCC5FEN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8724282 | 0.77 | KMT2A (0.33) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL7574482 | 0.77 | HPGD (0.33) | ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL2204507 | 0.75 | MEN1 (0.47) | ERCC5FEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8731814 | 0.75 | ABL1 (0.44) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8389663 | 0.74 | SMN1; SMN2 (0.36) | ERCC5FEN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7577840 | 0.74 | MAPK1 (0.37) | RAB9AALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL8491100 | 0.74 | L3MBTL1 (0.40) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7582286 | 0.74 | HPGD (0.40) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6748543 | 0.73 | ERCC5 (0.39) | ERCC5FEN1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |