SCHEMBL9520829

SCHEMBL9520829

CN(C)S(=O)(=O)n1c(C#N)nc(-c2ccc(Cl)cc2)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.39
ERBB2 P04626 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.36
PTGS1 P23219 1/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPK1 P28482 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM5A P29375 1/20 0.34
CYP1A2 P05177 3/20 0.34
USP2 O75604 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
ALOX15 P16050 2/20 0.34
CYP2C19 P33261 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932694 0.91 KMT2A (0.38) PTGS2ERBB2ALDH1A1HPGDNPSR1
SCHEMBL9323989 0.90 TSHR (0.49) ERBB2ALDH1A1HPGDNPSR1TSHR
SCHEMBL933896 0.89 ADORA1 (0.42) ALDH1A1HPGDTSHRLMNAMEN1
SCHEMBL933331 0.88 TSHR (0.34) PTGS2HPGDTSHRLMNAKMT2A
SCHEMBL9519740 0.82 PTGS2 (0.39) PTGS2ERBB2ALDH1A1HPGDNPSR1
SCHEMBL932277 0.81 PTGS2 (0.39) PTGS2ALDH1A1HPGDTSHRLMNA
SCHEMBL9519745 0.77 SMN1; SMN2 (0.33) KDM4ESMN1; SMN2GAA
SCHEMBL4858808 0.76 CYP1A2 (0.36) ERBB2ALDH1A1HPGDNPSR1LMNA
SCHEMBL9875589 0.74 HPGD (0.39) ALDH1A1HPGDNPSR1LMNAMEN1
SCHEMBL9074842 0.74 SMN1; SMN2 (0.42) ALDH1A1HPGDNPSR1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0298196-B1 IMIDAZOLE COMPOUNDS AND BIOCIDAL COMPOSITIONS COMPRISING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 1993-06-02 EP disclosed
US-4995898-A Imidazole compounds and biocidal composition comprising the same for controlling harmful organisms ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-02-26 US disclosed
EP-0298196-A1 Imidazole compounds and biocidal compositions comprising the same ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-01-11 EP disclosed