Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324776 | 1.00 | KDM4E (0.46) | KDM4ESMN1; SMN2FNTAFNTBCYP19A1 | |
| SCHEMBL9321485 | 0.93 | GAA (0.50) | KDM4ESMN1; SMN2CYP19A1GPBAR1GAA | |
| SCHEMBL9321480 | 0.93 | GAA (0.50) | KDM4ESMN1; SMN2CYP19A1GPBAR1GAA | |
| SCHEMBL4586157 | 0.86 | CTSL (0.55) | KDM4ESMN1; SMN2CTSLXDHCTBP2 | |
| SCHEMBL257218 | 0.86 | CTSL (0.55) | KDM4ESMN1; SMN2CTSLXDHCTBP2 | |
| SCHEMBL4586154 | 0.86 | CTSL (0.55) | KDM4ESMN1; SMN2CTSLXDHCTBP2 | |
| SCHEMBL14519360 | 0.84 | FNTA (0.44) | KDM4EFNTAFNTBCYP19A1GAA | |
| SCHEMBL23410797 | 0.82 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2ALDH1A1XDHCYP3A4 | |
| SCHEMBL6091876 | 0.82 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2ALDH1A1XDHCYP3A4 | |
| SCHEMBL6091878 | 0.82 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2ALDH1A1XDHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278090-B1 | 2-Aminoacetamide pyridinyl derivatives | FISONS CORP (US) | 1994-01-26 | — | — | EP | disclosed |
| US-4769466-A | 2-aminoacetamide pyridinyl derivatives | PENNWALT CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0278090-A2 | 2-Aminoacetamide pyridinyl derivatives | FISONS CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |