Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 6/20 | 0.49 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586154 | 1.00 | CTSL (0.55) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4586157 | 1.00 | CTSL (0.55) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL8407033 | 0.88 | MGLL (0.58) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL28302059 | 0.88 | LMNA (0.52) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4586342 | 0.86 | ALDH1A1 (0.51) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9324776 | 0.86 | KDM4E (0.46) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9324768 | 0.86 | KDM4E (0.46) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9321485 | 0.86 | GAA (0.50) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4587535 | 0.86 | SMN1; SMN2 (0.50) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL13853886 | 0.86 | KDM4E (0.54) | CTSLKDM4ESMN1; SMN2CTBP2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220133918-A1 | COXIB-DERIVED CONJUGATE COMPOUNDS AND METHODS OF USE THEREOF | Reiley Pharmaceuticals, Inc. | 2022-05-05 | — | — | US | disclosed |
| CN-108348906-B | Hydrogenation catalyst composition and method for producing same, and hydrogenated polymer and method for producing same | 旭化成株式会社 | 2021-03-30 | — | — | CN | disclosed |
| CN-108348906-A | Hydrogenation catalyst composition and method for producing same, and hydrogenated polymer and method for producing same | 旭化成株式会社 | 2018-07-31 | — | — | CN | disclosed |
| CN-104736574-B | The manufacture method and hydrogenation catalyst composition of hydrogenation catalyst composition | 旭化成株式会社 | 2017-08-08 | — | — | CN | disclosed |
| CN-104640629-B | Catalyst composition for hydrogenation and hydrogenation method using catalyst composition for hydrogenation | 旭化成株式会社 | 2017-05-24 | — | — | CN | disclosed |
| CN-104718026-B | Hydrogenation catalyst composition and hydrogenation method using said hydrogenation catalyst composition | 旭化成株式会社 | 2017-05-17 | — | — | CN | disclosed |
| US-9096739-B2 | Cellulose acetate film | SK INNOVATION CO., LTD. (KR) | 2015-08-04 | — | — | US | disclosed |
| US-9096739-B2 | Cellulose acetate film | SK INNOVATION CO., LTD. (KR) | 2015-08-04 | — | — | US | disclosed |
| CN-104736574-A | Method of producing hydrogenation catalyst composition and hydrogenation catalyst composition | ASAHI KASEI CHEMICALS CORP | 2015-06-24 | — | — | CN | disclosed |
| CN-104718026-A | Hydrogenation catalyst composition and hydrogenation method using said hydrogenation catalyst composition | ASAHI KASEI CHEMICALS CORP | 2015-06-17 | — | — | CN | disclosed |
| CN-104640629-A | Catalyst composition for hydrogenation and hydrogenation method using catalyst composition for hydrogenation | ASAHI KASEI CHEMICALS CORP | 2015-05-20 | — | — | CN | disclosed |
| US-20150053113-A1 | Cellulose Acetate Film | SK INNOVATION CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| US-20150053113-A1 | Cellulose Acetate Film | SK INNOVATION CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| WO-2012030117-A2 | CELLULOSE ACETATE FILM | SK INNOVATION CO.,LTD. (KR) | 2012-03-08 | — | — | WO | disclosed |
| US-7320978-B2 | Oxazole derivatives, preparation and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-01-22 | — | — | US | disclosed |
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-02-22 | — | — | US | disclosed |
| US-4194050-A | HYDROGENATING OXIMES HAVING AN ALPHA-HYDROGEN USING A RUTHENIUM CATALYST AND A CARBOXYLIC ANHYDRIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4190656-A | VIRICIDES, ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-26 | — | — | US | disclosed |
| US-4137417-A | Process for producing an enamide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133918-A1 | COXIB-DERIVED CONJUGATE COMPOUNDS AND METHODS OF USE THEREOF | PTGES2, PTGES, OPRK1 | CTSL 2269/4885KDM4E 3239/4885SMN1; SMN2 4409/4885 |
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | OXA1L, ARG2, CYP3A7 | CTSL 2413/4885KDM4E 2554/4885SMN1; SMN2 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.