Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 6/20 | 0.49 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257218 | 1.00 | CTSL (0.55) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4586157 | 1.00 | CTSL (0.55) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL8407033 | 0.88 | MGLL (0.58) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL28302059 | 0.88 | LMNA (0.52) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4586342 | 0.86 | ALDH1A1 (0.51) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9324776 | 0.86 | KDM4E (0.46) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9324768 | 0.86 | KDM4E (0.46) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL9321485 | 0.86 | GAA (0.50) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL4587535 | 0.86 | SMN1; SMN2 (0.50) | CTSLKDM4ESMN1; SMN2CTBP2XDH | |
| SCHEMBL13853886 | 0.86 | KDM4E (0.54) | CTSLKDM4ESMN1; SMN2CTBP2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479997-B | Synthetic method of 2, 3-diphenylquinoline | 湖南工程学院 | 2022-02-08 | — | — | CN | claimed |
| CN-112830913-A | Method for preparing 2, 5-furan diformylaldoxime | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | claimed |
| EP-1438300-A1 | METHOD FOR PREPARING BENZENESULFONYL COMPOUNDS | Pharmacia Corporation (US) | 2004-07-21 | — | — | EP | claimed |
| US-20030105334-A1 | Method for preparing benzenesulfonyl compounds | LETENDRE LEO J (US) | 2003-06-05 | — | — | US | claimed |
| WO-2003029230-A1 | METHOD FOR PREPARING BENZENESULFONYL COMPOUNDS | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | claimed |
| CN-112479997-B | Synthetic method of 2, 3-diphenylquinoline | 湖南工程学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-112830913-A | Method for preparing 2, 5-furan diformylaldoxime | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | disclosed |
| CN-110938043-A | Parecoxib sodium genotoxic impurity and preparation method thereof | 上海秀新臣邦医药科技有限公司 | 2020-03-31 | — | — | CN | disclosed |
| US-9096739-B2 | Cellulose acetate film | SK INNOVATION CO., LTD. (KR) | 2015-08-04 | — | — | US | disclosed |
| US-20150053113-A1 | Cellulose Acetate Film | SK INNOVATION CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| EP-1556364-A4 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ CORP (KR) | 2008-04-16 | — | — | EP | disclosed |
| US-7329401-B2 | Cyclooxygenase-2 selective agents useful as imaging probes and related methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1438300-A1 | METHOD FOR PREPARING BENZENESULFONYL COMPOUNDS | Pharmacia Corporation (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2004035553-A1 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ CORP. (KR) | 2004-04-29 | — | — | WO | disclosed |
| US-20040072884-A1 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP. (KR) | 2004-04-15 | — | — | US | disclosed |
| US-20030105334-A1 | Method for preparing benzenesulfonyl compounds | LETENDRE LEO J (US) | 2003-06-05 | — | — | US | disclosed |
| WO-2003029230-A1 | METHOD FOR PREPARING BENZENESULFONYL COMPOUNDS | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |
| US-5608069-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH GAMMA-AMINOBUTYRIC ACID | NOVO NORDISK A/S (DK) | 1997-03-04 | — | — | US | disclosed |
| US-5380854-A | Anticoagulants for surgery | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5254576-A | Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105334-A1 | Method for preparing benzenesulfonyl compounds | TST, PTGS2, STS | CTSL 2598/4885KDM4E 877/4885SMN1; SMN2 2104/4885 |
| US-20040072884-A1 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CYP3A5, CYP2C9, CYP2C19 | CTSL 4063/4885KDM4E 2784/4885SMN1; SMN2 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.