Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 8/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 2/20 | 0.32 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672604 | 0.86 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL14339054 | 0.86 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL9671381 | 0.86 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL8985076 | 0.86 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL7294590 | 0.86 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL9326904 | 0.84 | LMNA (0.42) | PDCD4 | |
| Benzene SCHEMBL9328037 | 0.84 | PDCD4 (0.45) | PDCD4DAGLAGLS2 | |
| SCHEMBL9745643 | 0.83 | PDCD4 (0.38) | PDCD4NAAACNR1DAGLA | |
| SCHEMBL9672430 | 0.83 | NAAA (0.40) | PDCD4NAAACNR1DAGLAPNLIP | |
| SCHEMBL8985069 | 0.83 | PDCD4 (0.39) | PDCD4NAAACNR1DAGLAGLS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322953-A | Antiinflammatory agents; intermediates for 2-furanone compounds | ALLERGAN, INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5298633-A | Silane intermediates | ALLERGAN, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5171863-A | 2-trialkylsily-4-substituted furan derivatives | ALLERGAN, INC. (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |