Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166914 | 0.91 | PLA2G2A (0.57) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9323915 | 0.90 | PLA2G2A (0.56) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9162948 | 0.86 | PLA2G2A (0.54) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9167645 | 0.86 | CNR2 (0.53) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9323941 | 0.86 | CNR2 (0.46) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL30036044 | 0.85 | PLA2G2A (0.53) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9402583 | 0.84 | PLA2G2A (0.52) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9402649 | 0.83 | PLA2G2A (0.51) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9324895 | 0.83 | PLA2G2A (0.51) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR | |
| SCHEMBL9169597 | 0.83 | PLA2G2A (0.51) | PLA2G2ACYP3A4TDP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374772-A | Skin disorders, antiinflammatory agents, cardiovascular disorders | HOFFMANN-LAROCHE INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0601385-A1 | Disubstituted benzoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |