Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166914 | 0.94 | PLA2G2A (0.57) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9325282 | 0.90 | PLA2G2A (0.52) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9323897 | 0.89 | PLA2G2A (0.54) | PLA2G2ATSHRMEN1KMT2ATP53 | |
| SCHEMBL9162948 | 0.89 | PLA2G2A (0.54) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9324877 | 0.89 | PLA2G2A (0.54) | PLA2G2ATSHRMEN1KMT2ATP53 | |
| SCHEMBL9325186 | 0.89 | PLA2G2A (0.54) | PLA2G2ATSHRMEN1KMT2ATP53 | |
| SCHEMBL9167645 | 0.89 | CNR2 (0.53) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9324895 | 0.89 | PLA2G2A (0.51) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL30036044 | 0.88 | PLA2G2A (0.53) | PLA2G2ATSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9325248 | 0.88 | PLA2G2A (0.70) | PLA2G2ATSHRMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374772-A | Skin disorders, antiinflammatory agents, cardiovascular disorders | HOFFMANN-LAROCHE INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0601385-A1 | Disubstituted benzoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |