Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326379 | 0.83 | KCNH2 (0.50) | ALDH1A1KCNH2PTGS2GAAMAPT | |
| SCHEMBL9327633 | 0.77 | KCNH2 (0.50) | ALDH1A1KCNH2MAPTTSHR | |
| SCHEMBL9324472 | 0.74 | CA1 (0.42) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL9324328 | 0.73 | TMEM97 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL9327453 | 0.72 | KCNH2 (0.55) | ALDH1A1KCNH2MAPTMEN1KMT2A | |
| SCHEMBL6182358 | 0.71 | GAA (0.47) | HTR2AALDH1A1KCNH2PTGS2GAA | |
| SCHEMBL6377951 | 0.69 | HTR2A (0.49) | HTR2AALDH1A1PTGS2GAAMAPT | |
| SCHEMBL6377945 | 0.69 | HTR2A (0.49) | HTR2AALDH1A1PTGS2GAAMAPT | |
| SCHEMBL20804967 | 0.68 | MEN1 (0.49) | HTR2AALDH1A1GAAMAPTMEN1 | |
| SCHEMBL29408485 | 0.68 | MEN1 (0.49) | HTR2AALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |