Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325760 | 0.87 | CA12 (0.46) | CA1CA2ALDH1A1SIGMAR1 | |
| SCHEMBL9325729 | 0.84 | CYP2C9 (0.45) | ALDH1A1MAPTGAASIGMAR1LMNA | |
| SCHEMBL9324328 | 0.81 | TMEM97 (0.48) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL9327633 | 0.79 | KCNH2 (0.50) | ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL9326379 | 0.78 | KCNH2 (0.50) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10683290 | 0.75 | ALDH1A1 (0.65) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL9325692 | 0.74 | HTR2A (0.36) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL1674065 | 0.73 | SIGMAR1 (0.68) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL9327453 | 0.72 | KCNH2 (0.55) | MEN1KMT2AALDH1A1MAPTSIGMAR1 | |
| SCHEMBL7035347 | 0.70 | TSHR (0.65) | CA1CA2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |