Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327603 | 0.86 | LMNA (0.53) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9326050 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL9324472 | 0.81 | CA1 (0.42) | SIGMAR1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL9327633 | 0.79 | KCNH2 (0.50) | SIGMAR1MAPTALDH1A1 | |
| SCHEMBL9326379 | 0.78 | KCNH2 (0.50) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9324352 | 0.77 | ALDH1A1 (0.47) | TMEM97SIGMAR1MAPTALDH1A1KDM4E | |
| SCHEMBL9325692 | 0.73 | HTR2A (0.36) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL3570124 | 0.73 | LMNA (0.65) | TMEM97SIGMAR1MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9053101 | 0.72 | LMNA (0.66) | TMEM97SIGMAR1MAPTALDH1A1KDM4E | |
| SCHEMBL9327453 | 0.71 | KCNH2 (0.55) | SIGMAR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |