Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324295 | 0.87 | KCNH2 (0.49) | KCNH2HTTKMT2AMEN1NPSR1 | |
| SCHEMBL9326409 | 0.83 | SIGMAR1 (0.39) | KMT2AALDH1A1TRPM8MAPT | |
| SCHEMBL9327633 | 0.82 | KCNH2 (0.50) | KCNH2ALDH1A1MAPT | |
| SCHEMBL10531208 | 0.75 | KCNH2 (0.65) | KCNH2ALDH1A1MAPT | |
| SCHEMBL9327453 | 0.74 | KCNH2 (0.55) | KCNH2KMT2AMEN1THRBALDH1A1 | |
| Bromide SCHEMBL11237734 | 0.72 | KCNH2 (0.56) | KCNH2ALDH1A1MAPTLMNA | |
| SCHEMBL11222756 | 0.72 | KCNH2 (0.71) | KCNH2THRBALDH1A1MAPT | |
| Oxalic Acid SCHEMBL11228627 | 0.71 | KCNH2 (0.59) | KCNH2KMT2AMEN1THRBALDH1A1 | |
| SCHEMBL9325771 | 0.71 | KCNH2 (0.50) | KCNH2KMT2AMAPT | |
| SCHEMBL5632454 | 0.71 | KCNH2 (0.83) | KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |