Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 15/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179120 | 0.95 | MAPT (0.43) | FPR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9180769 | 0.89 | SMN1; SMN2 (0.48) | FPR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1744281 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9325535 | 0.84 | FPR2 (0.47) | FPR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9183532 | 0.83 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9186302 | 0.83 | XDH (0.47) | FPR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9325828 | 0.82 | MAPT (0.47) | FPR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7416710 | 0.81 | FPR2 (0.48) | FPR2ENPP1 | |
| SCHEMBL9187036 | 0.81 | GAK (0.44) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21823381 | 0.79 | FPR2 (0.58) | FPR2ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581805-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992019602-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |
| EP-0469013-A1 | NOVEL ARYLPYRIDAZINES, THEIR MANUFACTURE, USE AND MEDICAMENTS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1992-02-05 | — | — | EP | disclosed |