Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 11/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616208 | 0.85 | MAPT (0.44) | MAPTUSP2ALOX15TSHRFPR2 | |
| SCHEMBL9325535 | 0.84 | FPR2 (0.47) | MAPTFPR2MEN1KMT2AALDH1A1 | |
| SCHEMBL9325859 | 0.82 | FPR2 (0.47) | MAPTFPR2MEN1KMT2AALDH1A1 | |
| SCHEMBL9185156 | 0.81 | MAPT (0.44) | MAPTUSP2ALOX15TSHRFPR2 | |
| SCHEMBL9264673 | 0.81 | MAPT (0.44) | MAPTUSP2ALOX15TSHRAGTR1 | |
| SCHEMBL9268561 | 0.79 | TRPC6 (0.46) | MAPTUSP2FPR2MEN1KMT2A | |
| SCHEMBL9266782 | 0.77 | PDE4D (0.54) | MAPTUSP2ALOX15TSHRAGTR1 | |
| SCHEMBL9179120 | 0.76 | MAPT (0.43) | MAPTUSP2FPR2MEN1KMT2A | |
| SCHEMBL9180526 | 0.75 | MAPT (0.48) | MAPTUSP2ALOX15TSHRFPR2 | |
| SCHEMBL9616213 | 0.73 | FPR2 (0.41) | MAPTUSP2ALOX15TSHRFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581805-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992019602-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |