Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.47 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268561 | 0.95 | TRPC6 (0.46) | FPR2TRPC6MEN1ALDH1A1MAPT | |
| SCHEMBL1752782 | 0.85 | ALDH1A1 (0.50) | MEN1ALDH1A1MAPTKMT2APDE4B | |
| SCHEMBL9324686 | 0.85 | FPR2 (0.46) | FPR2TRPC6MEN1ALDH1A1MAPT | |
| SCHEMBL9325828 | 0.84 | MAPT (0.47) | FPR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9325859 | 0.84 | FPR2 (0.47) | FPR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9257719 | 0.83 | XDH (0.53) | FPR2TRPC6MEN1ALDH1A1MAPT | |
| SCHEMBL12989431 | 0.83 | ALDH1A1 (0.42) | MEN1ALDH1A1MAPTKMT2APDE4B | |
| SCHEMBL9265518 | 0.79 | TRPC6 (0.50) | FPR2TRPC6ALDH1A1PDE4B | |
| SCHEMBL9179120 | 0.78 | MAPT (0.43) | FPR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9267049 | 0.78 | PDE4A (0.43) | FPR2MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581805-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992019602-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |