Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325797 | 0.83 | KDM4E (0.40) | LMNARECQLKDM4ECACNA1FCHRM2 | |
| SCHEMBL9324412 | 0.83 | TRPM8 (0.35) | LMNARECQLDRD3KCNH2MAPT | |
| SCHEMBL9324295 | 0.80 | KCNH2 (0.49) | KCNH2MAPTHTTPOLBALDH1A1 | |
| SCHEMBL9324382 | 0.72 | KDM4E (0.39) | LMNARECQLKDM4ECACNA1FCHRM2 | |
| SCHEMBL10896046 | 0.72 | KCNH2 (0.53) | LMNARECQLKDM4ECACNA1FCHRM2 | |
| SCHEMBL9326142 | 0.71 | LMNA (0.47) | LMNARECQLKDM4EMLNRCACNA1F | |
| SCHEMBL3719859 | 0.71 | KCNH2 (0.57) | LMNAKDM4ECACNA1FCHRM2DRD3 | |
| SCHEMBL9326136 | 0.70 | LMNA (0.42) | LMNARECQLKDM4EMLNRKCNH2 | |
| SCHEMBL10878888 | 0.69 | KCNH2 (0.54) | LMNAKDM4ECACNA1FCHRM2DRD3 | |
| SCHEMBL9624530 | 0.69 | KDM4E (0.58) | LMNARECQLKDM4ECACNA1FCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |