Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | PRKACG | P22612 | 1/20 | 0.59 |
| ▸ | PRKACB | P22694 | 1/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543732 | 0.78 | PRKACA (0.47) | PRKACAPRKACGPRKACBCACNA1GALDH1A1 | |
| SCHEMBL3959703 | 0.77 | KDM1A (0.43) | PRKACAPRKACGPRKACBNOTUM | |
| SCHEMBL3956182 | 0.77 | KDM1A (0.43) | PRKACAPRKACGPRKACBNOTUM | |
| SCHEMBL3956185 | 0.77 | KDM1A (0.43) | PRKACAPRKACGPRKACBNOTUM | |
| SCHEMBL21185307 | 0.77 | SCD5 (0.55) | ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8479255 | 0.76 | ALDH1A1 (0.50) | PRKACAPRKACGPRKACBCACNA1GALDH1A1 | |
| SCHEMBL28732543 | 0.76 | EGFR (0.38) | PRKACAPRKACGPRKACBNOTUM | |
| SCHEMBL28162635 | 0.75 | PRKACA (0.45) | PRKACAPRKACGPRKACBCACNA1GALDH1A1 | |
| SCHEMBL12673845 | 0.75 | KMT2A (0.43) | PRKACAPRKACGPRKACBNOTUMTSHR | |
| SCHEMBL3756970 | 0.75 | CACNA1G (0.48) | CACNA1GNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288749-A | Treating central nervous system or cardiovascular disorders | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |