Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169318 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ROCK1MYLK4 | |
| SCHEMBL6055220 | 0.79 | MEN1 (0.43) | ALDH1A1ROCK1MYLK4 | |
| SCHEMBL9326757 | 0.79 | MEN1 (0.43) | ALDH1A1ROCK1MYLK4 | |
| SCHEMBL2169288 | 0.77 | CYP2C19 (0.34) | NOS2ROCK1MYLK4 | |
| SCHEMBL2583496 | 0.70 | NOS2 (0.45) | NOS2ROCK1 | |
| SCHEMBL1560439 | 0.68 | AKT2 (0.41) | ROCK1MYLK4 | |
| SCHEMBL2170615 | 0.67 | ROCK2 (0.34) | NOS2ROCK1 | |
| SCHEMBL2169327 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL30954596 | 0.67 | NOS2 (0.41) | NOS2ALDH1A1ROCK1MYLK4 | |
| SCHEMBL2170780 | 0.66 | ALDH1A1 (0.36) | NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | NOS2 671/4885ALDH1A1 516/4885PIM1 170/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | NOS2 671/4885ALDH1A1 516/4885PIM1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.