Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923273 | 0.84 | CNR2 (0.51) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL9326006 | 0.83 | CA12 (0.41) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL9325952 | 0.82 | ALDH1A1 (0.45) | MAPTPPARGPPARAALDH1A1HPGD | |
| SCHEMBL539076 | 0.82 | PIN1 (0.51) | CYP3A4PIN1MAPTTHRBPOLB | |
| SCHEMBL1634402 | 0.81 | KIF11 (0.43) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL5679931 | 0.81 | KIF11 (0.43) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL5389423 | 0.81 | CNR2 (0.40) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL5379797 | 0.81 | CNR2 (0.40) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL6718331 | 0.81 | CNR2 (0.40) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL17420520 | 0.80 | ACSS2 (0.47) | CNR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298511-A | Alkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-29 | — | — | US | disclosed |
| EP-0540165-A1 | Alkanoic acid derivatives | ZENECA LIMITED (GB) | 1993-05-05 | — | — | EP | disclosed |