Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 12/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12414160 | 0.86 | GAA (0.49) | PLK1FAAH | |
| SCHEMBL9326201 | 0.85 | PLK1 (0.62) | PLK1FAAHLMNACYP1A2CYP2C19 | |
| SCHEMBL12417397 | 0.84 | MAPT (0.51) | PLK1FAAH | |
| SCHEMBL12680148 | 0.83 | PLK1 (0.49) | PLK1FAAHKMT2A | |
| SCHEMBL14753644 | 0.83 | FAAH (0.49) | PLK1FAAHL3MBTL1 | |
| SCHEMBL12893245 | 0.82 | ALDH1A1 (0.51) | PLK1LMNAMAPK1KMT2A | |
| SCHEMBL5964408 | 0.79 | L3MBTL1 (0.56) | PLK1L3MBTL1LMNACYP1A2MAPK1 | |
| SCHEMBL8984333 | 0.79 | L3MBTL1 (0.56) | PLK1FAAHL3MBTL1LMNACYP1A2 | |
| SCHEMBL5964415 | 0.79 | L3MBTL1 (0.59) | PLK1FAAHL3MBTL1LMNACYP1A2 | |
| SCHEMBL11962158 | 0.79 | PLK1 (1.00) | PLK1L3MBTL1LMNACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5365691-A | Methods and agents for combating cockroaches | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-22 | — | — | US | disclosed |