SCHEMBL12417397

SCHEMBL12417397

CNC(=O)Oc1ccc(OCCOC)cc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.51
PLK1 P53350 2/20 0.50
RAB9A P51151 1/20 0.46
FAAH O00519 9/20 0.46
ACHE P22303 2/20 0.44
ACACB O00763 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12680148 0.92 PLK1 (0.49) MAPTPLK1FAAHACHEACACB
SCHEMBL12418675 0.84 ALDH1A1 (0.44) MAPTPLK1RAB9AFAAHACHE
SCHEMBL9327664 0.84 PLK1 (0.65) PLK1FAAH
SCHEMBL12414160 0.84 GAA (0.49) MAPTPLK1FAAHACHEALDH1A1
SCHEMBL14753644 0.81 FAAH (0.49) PLK1FAAHACHE
SCHEMBL12893245 0.81 ALDH1A1 (0.51) MAPTPLK1RAB9AACHEALDH1A1
SCHEMBL4751488 0.81 PLK1 (0.75) MAPTPLK1RAB9A
SCHEMBL9326201 0.80 PLK1 (0.62) MAPTPLK1RAB9AFAAHALDH1A1
SCHEMBL26698250 0.80 LMNA (0.53) MAPTRAB9AACACBALDH1A1
SCHEMBL9326191 0.77 SMN1; SMN2 (0.59) PLK1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110171162-A1 POLYMER CONJUGATES OF THYMOSIN ALPHA 1 PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171162-A1 POLYMER CONJUGATES OF THYMOSIN ALPHA 1 PEPTIDES TMSB4X, TMSB10, TAP1 MAPT 837/4885PLK1 2245/4885RAB9A 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.