Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592654 | 1.00 | CTSL (0.54) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL9256682 | 0.98 | CTSL (0.54) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL9732240 | 0.92 | ACE (0.51) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL9175234 | 0.86 | ACE (0.60) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9176326 | 0.86 | ACE (0.60) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL10591582 | 0.85 | ACE (0.64) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9327739 | 0.85 | CTSL (0.49) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL9775244 | 0.85 | ACE (0.56) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL9775237 | 0.85 | ACE (0.56) | CTSLACEKMT2AMEN1CYP3A4 | |
| SCHEMBL12684557 | 0.84 | FKBP1A (0.46) | CTSLACEKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |