Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.59 |
| ▸ | PRKDC | P78527 | 2/20 | 0.59 |
| ▸ | GABRP | O00591 | 5/20 | 0.55 |
| ▸ | GABRD | O14764 | 5/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.55 |
| ▸ | GABRE | P78334 | 5/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327677 | 0.91 | CYP2D6 (0.53) | CYP1A2CYP1A1CYP1B1PRKDCGABRP | |
| SCHEMBL9327900 | 0.89 | CYP1A2 (0.56) | CYP1A2CYP1A1CYP1B1PRKDCGABRP | |
| Mitoflaxone SCHEMBL106705 | 0.89 | CYP1A2 (0.62) | CYP1A2CYP1A1CYP1B1PRKDCGABRP | |
| SCHEMBL9327546 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP1A1CYP1B1PRKDCCYP2D6 | |
| SCHEMBL12835503 | 0.86 | CYP1A2 (0.60) | CYP1A2CYP1A1CYP1B1PRKDCGABRP | |
| SCHEMBL7083153 | 0.85 | CYP2D6 (0.54) | CYP1A2CYP1A1CYP1B1PRKDCCYP2D6 | |
| SCHEMBL9328729 | 0.85 | CYP2D6 (0.49) | CYP1A2CYP1A1CYP1B1PRKDCCYP2D6 | |
| SCHEMBL7083117 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP1A1CYP1B1PRKDCGABRP | |
| SCHEMBL12835531 | 0.85 | CYP1A2 (0.54) | CYP1A2CYP1A1CYP1B1PRKDCCYP2D6 | |
| SCHEMBL9328769 | 0.84 | CYP1A2 (0.63) | CYP1A2CYP1A1CYP1B1PRKDCGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | claimed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | claimed |
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | disclosed |