Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329537 | 0.96 | TARBP2 (0.42) | KDM4EPOLBTARBP2USP2HSD17B10 | |
| SCHEMBL9328127 | 0.93 | NPSR1 (0.41) | KDM4EPOLBTARBP2USP2HSD17B10 | |
| SCHEMBL9330285 | 0.90 | POLB (0.51) | KDM4EPOLBTARBP2USP2HSD17B10 | |
| SCHEMBL9329600 | 0.89 | CYP3A4 (0.40) | KDM4EHSD17B10CYP3A4ALOX15SMN1; SMN2 | |
| SCHEMBL9329585 | 0.88 | LMNA (0.39) | HSD17B10CYP3A4ALOX15SMN1; SMN2TDP1 | |
| SCHEMBL9327972 | 0.86 | LMNA (0.42) | POLBHSD17B10CYP3A4ALOX15 | |
| SCHEMBL9328253 | 0.86 | KDM4E (0.40) | KDM4EPOLBHSD17B10CYP3A4ALOX15 | |
| Bifendate SCHEMBL29516235 | 0.85 | TARBP2 (0.48) | KDM4EPOLBTARBP2USP2HSD17B10 | |
| Bifendate SCHEMBL30788692 | 0.85 | TARBP2 (0.48) | KDM4EPOLBTARBP2USP2HSD17B10 | |
| Bifendate SCHEMBL896166 | 0.85 | TARBP2 (0.48) | KDM4EPOLBTARBP2USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267970-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5264594-A | Alkylation of carbonates | TSUMURA & CO. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4996331-A | Novel biphenyl derivative and preparation and use thereof | TSUMURA & CO. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4925872-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4849448-A | LIVER DISORDER TREATMENT | TSUMURA JUNTENDO, INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0267970-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-05-25 | — | — | EP | disclosed |