Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328253 | 0.96 | KDM4E (0.40) | CYP3A4ALOX15PKMKDM4ETSHR | |
| SCHEMBL9329569 | 0.90 | PKM (0.46) | CYP3A4ALOX15PKMKDM4EHSD17B10 | |
| SCHEMBL9328107 | 0.89 | KDM4E (0.45) | CYP3A4ALOX15KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL9329537 | 0.86 | TARBP2 (0.42) | CYP3A4ALOX15KDM4EHSD17B10BPTF | |
| SCHEMBL9329585 | 0.85 | LMNA (0.39) | CYP3A4ALOX15TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9094972 | 0.84 | LCK (0.46) | CYP3A4ALOX15PKMKDM4ETSHR | |
| SCHEMBL9328127 | 0.83 | NPSR1 (0.41) | CYP3A4ALOX15KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL9327972 | 0.82 | LMNA (0.42) | CYP3A4ALOX15TSHRHSD17B10MEN1 | |
| SCHEMBL9603034 | 0.80 | CYP3A4 (0.43) | CYP3A4ALOX15PKMKDM4ESMN1; SMN2 | |
| SCHEMBL9330285 | 0.79 | POLB (0.51) | CYP3A4ALOX15KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267970-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5264594-A | Alkylation of carbonates | TSUMURA & CO. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4996331-A | Novel biphenyl derivative and preparation and use thereof | TSUMURA & CO. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4925872-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4849448-A | LIVER DISORDER TREATMENT | TSUMURA JUNTENDO, INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0267970-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-05-25 | — | — | EP | disclosed |