Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933038 | 0.83 | NPSR1 (0.55) | LMNASMN1; SMN2GAAHTTHRH1 | |
| SCHEMBL22300397 | 0.81 | TDP1 (0.51) | KDM4EPOLBTSHRTDP1LMNA | |
| SCHEMBL8797884 | 0.79 | HRH1 (0.51) | LMNASMN1; SMN2HRH1CYP1A2CYP2C19 | |
| SCHEMBL788202 | 0.78 | HRH1 (0.45) | KDM4ETDP1LMNASMN1; SMN2GAA | |
| SCHEMBL29167622 | 0.77 | KDM4E (0.44) | KDM4EPOLBTSHRTDP1LMNA | |
| SCHEMBL165452 | 0.75 | TRPA1 (0.55) | TSHRTDP1HTTTRPA1BACE1 | |
| SCHEMBL3702884 | 0.75 | KDM4E (0.44) | KDM4EPOLBTSHRTDP1LMNA | |
| SCHEMBL798358 | 0.74 | CYP2C19 (0.46) | KDM4ETDP1LMNASMN1; SMN2GAA | |
| SCHEMBL1025193 | 0.74 | TRPA1 (0.53) | KDM4ETSHRTDP1LMNAHTT | |
| SCHEMBL934115 | 0.73 | KDM4E (0.45) | KDM4ETSHRTDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |