Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798358 | 0.88 | CYP2C19 (0.46) | NPSR1HRH1RECQLGAACYP2C19 | |
| SCHEMBL788202 | 0.84 | HRH1 (0.45) | HRH1GAACYP2C19CYP1A2SMN1; SMN2 | |
| SCHEMBL932822 | 0.83 | KDM4E (0.47) | NPSR1HRH1MEN1KMT2AGAA | |
| SCHEMBL8797884 | 0.81 | HRH1 (0.51) | HRH1CYP2C19CYP1A2SMN1; SMN2HRH3 | |
| SCHEMBL29150535 | 0.80 | AMY1A (0.59) | NPSR1MEN1KMT2AGAAMAPT | |
| SCHEMBL3648829 | 0.79 | NPSR1 (0.55) | NPSR1RECQLMEN1KMT2AGAA | |
| SCHEMBL24708602 | 0.78 | HRH1 (0.51) | NPSR1HRH1RECQLCYP2C19CYP2D6 | |
| SCHEMBL18549344 | 0.77 | MAPT (0.61) | NPSR1RECQLMEN1KMT2AGAA | |
| SCHEMBL29167681 | 0.76 | NPSR1 (0.45) | NPSR1HRH1RECQLMEN1KMT2A | |
| SCHEMBL8400715 | 0.75 | AMY1A (0.57) | NPSR1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |