Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933038 | 0.88 | NPSR1 (0.55) | CYP2C19SMN1; SMN2CYP1A2NPSR1HRH1 | |
| SCHEMBL788202 | 0.84 | HRH1 (0.45) | CYP2C19SMN1; SMN2CYP1A2HRH1HRH3 | |
| SCHEMBL798050 | 0.82 | ESR1 (0.58) | KDM4EGAAALDH1A1RAB9A | |
| SCHEMBL8797884 | 0.81 | HRH1 (0.51) | CYP2C19SMN1; SMN2CYP1A2HRH1HRH3 | |
| SCHEMBL934115 | 0.81 | KDM4E (0.45) | CYP2C19SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28858657 | 0.80 | TYR (0.53) | LMNAGAAHTTALDH1A1ALOX15 | |
| SCHEMBL24708602 | 0.78 | HRH1 (0.51) | CYP2C19SMN1; SMN2CYP1A2NPSR1HRH1 | |
| SCHEMBL933437 | 0.78 | KDM4E (0.42) | CYP2C19SMN1; SMN2CYP1A2HRH1CYP2D6 | |
| SCHEMBL7065825 | 0.76 | ESR1 (0.50) | SMN1; SMN2ALOX15RAB9A | |
| SCHEMBL12475666 | 0.75 | TYR (0.60) | HRH1LMNAKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615930-A2 | TASTE ENHANCEMENT | Givaudan SA (CH) | 2013-07-24 | — | — | EP | disclosed |
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2012035032-A2 | TASTE ENHANCEMENT | GIVAUDAN SA (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |