Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933038 | 0.84 | NPSR1 (0.55) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL798358 | 0.84 | CYP2C19 (0.46) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL8797884 | 0.79 | HRH1 (0.51) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL932822 | 0.78 | KDM4E (0.47) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL798050 | 0.77 | ESR1 (0.58) | KDM4EGAAALDH1A1 | |
| SCHEMBL934115 | 0.76 | KDM4E (0.45) | SMN1; SMN2CYP1A2CYP2C19LMNAKDM4E | |
| SCHEMBL29485637 | 0.76 | HRH1 (0.69) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL231470 | 0.76 | HRH1 (0.69) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| Hydrochloric Acid SCHEMBL841530 | 0.74 | HRH1 (0.67) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 | |
| SCHEMBL5961501 | 0.74 | HRH1 (0.67) | HRH1SMN1; SMN2CYP1A2CYP2C19HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | claimed |
| EP-2615930-A2 | TASTE ENHANCEMENT | Givaudan SA (CH) | 2013-07-24 | — | — | EP | disclosed |
| EP-2531489-A1 | OXALAMIDE DERIVATIVE AS UMAMI FLAVOURING AGENT | Givaudan SA (CH) | 2012-12-12 | — | — | EP | disclosed |
| WO-2012035032-A2 | TASTE ENHANCEMENT | GIVAUDAN SA (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011095533-A1 | OXALAMIDE DERIVATIVE AS UMAMI FLAVOURING AGENT | GIVAUDAN SA (CH) | 2011-08-11 | — | — | WO | disclosed |