Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102071 | 0.83 | ABL1 (0.47) | KMT2AMEN1POLBUSP7MAPT | |
| SCHEMBL1501857 | 0.81 | ALDH1A1 (0.50) | KMT2AMEN1BACE1MAPK1MAPT | |
| SCHEMBL21647122 | 0.80 | ALDH1A1 (0.38) | KMT2AMEN1TDP1LMNAMAPK1 | |
| SCHEMBL2406494 | 0.79 | KMT2A (0.42) | KMT2AMEN1TDP1LMNANPC1 | |
| SCHEMBL2565144 | 0.79 | TDP1 (0.35) | KMT2AMEN1POLBACHESYK | |
| SCHEMBL6881481 | 0.78 | HPGD (0.36) | COMTKMT2AMEN1POLBACHE | |
| SCHEMBL7705609 | 0.78 | MEN1 (0.33) | COMTKMT2AMEN1POLBACHE | |
| SCHEMBL4193418 | 0.77 | PDCD1 (0.34) | COMTKMT2AMEN1POLBSYK | |
| SCHEMBL7818368 | 0.76 | RAB9A (0.38) | KMT2AMEN1POLBACHESYK | |
| SCHEMBL7805516 | 0.76 | PTGS2 (0.36) | KMT2AMEN1POLBACHESYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378295-B1 | Flame retardant composition and method of use | ALBRIGHT & WILSON (GB) | 1994-03-09 | — | — | EP | disclosed |
| EP-0378295-A2 | Flame retardant composition and method of use | Albright & Wilson Limited (GB) | 1990-07-18 | — | — | EP | disclosed |