SCHEMBL8102071

SCHEMBL8102071

Oc1ccc(-c2ccc[c]c2O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.47
ABCB1 P08183 2/20 0.47
BCR P11274 2/20 0.47
ESR2 Q92731 3/20 0.42
ESR1 P03372 5/20 0.42
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
USP7 Q93009 4/20 0.36
RPS6KA3 P51812 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1501857 0.84 ALDH1A1 (0.50) ABL1ABCB1BCRESR2MMP3
SCHEMBL9328286 0.83 COMT (0.40) MEN1KMT2AUSP7POLBMAPT
SCHEMBL21647122 0.83 ALDH1A1 (0.38) ABL1ABCB1BCRBCL2L1MEN1
SCHEMBL6056277 0.81 ABL1 (0.45) ABL1ABCB1BCRESR2ESR1
SCHEMBL2406494 0.79 KMT2A (0.42) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL11655392 0.79 EGFR (0.43) BCL2L1
SCHEMBL6824951 0.78 HSD17B1 (0.48) ESR2ESR1RPS6KA3ADORA1HSD17B1
SCHEMBL6373451 0.75 ALOX5 (0.45) ESR2ESR1HSD17B1HSD17B2POLB
SCHEMBL18547650 0.75 KIF11 (0.42) ABL1ABCB1BCRESR2ESR1
SCHEMBL28140406 0.75 ABL1 (0.49) ABL1ABCB1BCRESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6133190-A SUPPORTED MERCAPTOAKYL-SUBSTITUTED POLYSTYRENESULFONATE IS USED AS A CATALYST FOR CONDENSATION OF ALDEHYDE OR KETONE WITH PHENOL TO FORM DIHYDROXY COMPOUND THE DOW CHEMICAL COMPANY (US) 2000-10-17 US disclosed
US-6051658-A A POLYSTYRENE HAVING MERCAPTOSULFONIC ACID RESIDUE, USEFUL AS CATALYST THE DOW CHEMICAL COMPANY (US) 2000-04-18 US disclosed
US-5939494-A CATALYST USEFUL FOR THE CONDENSATION OF AN ALDEHYDE OR KETONE STARTING MATERIAL WITH A PHENOL IS AN INSOLUBLE MERCAPTOSULFONIC ACID COMPOUND THE DOW CHEMICAL COMPANY (US) 1999-08-17 US disclosed
US-5463140-A Condensing aldehyde or ketone with phenol in presence of soluble or insoluble mercaptosulfonic acid compound to form geminal bisphenol moiety at each aldehyde or ketone moiety THE DOW CHEMICAL COMPANY (US) 1995-10-31 US disclosed
US-5112730-A Films, colorfastness FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed