Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156739 | 0.74 | LMNA (0.47) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL5966693 | 0.72 | ALDH1A1 (0.74) | HDAC6HSD17B10KDM4EALOX15ALDH1A1 | |
| SCHEMBL10304515 | 0.72 | HDAC1 (0.48) | HDAC1HDAC6KDM4EALDH1A1HPGD | |
| SCHEMBL7490899 | 0.72 | HDAC1 (0.45) | HDAC1HDAC6HSD17B10PTGS2ALDH1A1 | |
| SCHEMBL15024362 | 0.71 | TSHR (0.69) | ALDH1A1RAB9ATSHR | |
| SCHEMBL15330324 | 0.71 | GAA (0.42) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL15156844 | 0.70 | HSD17B10 (0.47) | HSD17B10KDM4EALOX15PTGS2ALDH1A1 | |
| Bicarbonate SCHEMBL9488633 | 0.70 | SMN1; SMN2 (0.50) | HDAC1HDAC6ALDH1A1TSHR | |
| SCHEMBL8947261 | 0.70 | ALDH1A1 (0.75) | HDAC6HSD17B10KDM4EALOX15ALDH1A1 | |
| SCHEMBL7111748 | 0.70 | KDM4E (0.51) | HSD17B10KDM4EALOX15PTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336682-A | Heterocyclic compounds as fungicides | IMPERIAL CHEMICAL INDUSTRIES PUBLIC LIMITED COMPANY (GB) | 1994-08-09 | — | — | US | disclosed |
| US-5091407-A | HETEROCYCLIC COMPOUNDS AS FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0206523-B1 | HETEROCYCLIC COMPOUNDS AS FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| EP-0206523-A1 | Heterocyclic compounds as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |